Trust your gut? Definitely. Research shows that your gut and all its good-for-you microbes (bacteria, fungi, etc.) play an essential role in your overall health, from digestion and metabolism to your central nervous system and brain function. That’s why nourishing it with the highest quality probiotics is key to a healthier, more vibrant you.

Part of a well-rounded approach to fire up metabolism and reduce body mass

You are what you eat—but we’re not just talking about veggies, salads, and fiber-rich meals. Along with a healthy diet and regular exercise, consuming probiotics can have a positive impact on your weight, too.

Routine uses Bifidobacterium lactis B-420, a well-researched strain that populates your gut microbiome with beneficial bacteria, including Christensenellaceae (reduces waist circumference and body mass1, and boosts metabolism2) and Lactobacillus3 (helps regulate weight).

The science behind B. lactis B-420 is significant. One of the most telling human studies was a randomized, double-blind, placebo-controlled study of obese and overweight adults. B-420 showed improvements across the board compared to a placebo4, backing up similar results from previous scientific research on experimental animals5.

In the human study, among those who took B-420, there were greater changes in total body, trunk, and abdominal fat mass—making it a powerful tool for controlling fat in that hard-to-target midsection. There was also a 2.4% difference in change in waist circumference between those who took B-420 versus those who took a placebo, as well as increased plasma cortisol4, which has been linked to calorie burn and the breaking down of fatty acids—two key markers of fighting inflammation.


Hibberd A, Yde C, Ziegler M et al. Probiotic or synbiotic alters the gut microbiota and metabolism in a randomised controlled trial of weight management in overweight adultsBenef Microbes. 2019;10(2):121-135. doi:10.3920/bm2018.0028

2 Waters JL, Ley RE. The human gut bacteria Christensenellaceae are widespread, heritable, and associated with healthBMC Biol. 2019;17(1):83. doi:10.1186/s12915-019-0699-4

3 Rosing J, Walker K, Jensen B, Heitmann B. Oral Lactobacillus counts predict weight gain susceptibility: a 6-year follow-up studyObes Facts. 2017;10(5):473-482. doi:10.1159/000478095

4 Stenman L, Lehtinen M, Meland N et al. Probiotic with or without fiber controls body fat mass, associated with serum zonulin, in overweight and obese adults—randomized controlled trialEBioMedicine. 2016;13:190-200. doi:10.1016/j.ebiom.2016.10.036

5 Stenman L, Waget A, Garret C, Klopp P, Burcelin R, Lahtinen S. Potential probiotic Bifidobacterium animalisssp.lactis420 prevents weight gain and glucose intolerance in diet-induced obese miceBenef Microbes. 2014;5(4):437-445. doi:10.3920/bm2014.0014